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Engineering
GATE
School
Pharmacy
Competitive Exams
Intermediate
General
PHARMACEUTICS -1
Introduction of different dosage forms
3
Their classification with examples-their relative applications
Familiarization with new drug delivery systems
Introduction to Pharmacopoeias with special reference to the Indian Pharmacopoeia.
Metrology
4
System of weights and measures
Calculations including conversion from one to another system
Percentage calculations and adjustment of products
.Use of alligation method in calculations.Isotonic solutions.
Packaging of pharmaceuticals
7
Desirable features of a container and types of containers
Study of glass &plastics as materials for containers and rubber as a material for closure-their merits and demerits
Introduction to aerosol packaging
Size reduction, objectives, and factors affecting size reduction
methods of size reduction
study of Hammer mill, ball mill
Study of Fluid energy mill and Disintegrator
Size separation
4
size separation by sifting
Official standards for powders
Sedimentation methods of size separation
Construction and working of Cyclone separator
Mixing and Homogenization
5
Liquid mixing and powder mixing ,Mixing of semisolids
Study of silverson Mixer-Homogenizer, planetary Mixer
Triple Roller Mill,Propeller Mixer,
colloid Mill and Hand Homogeniser
Double cone mixer
Clarification and Filtration
3
Theory of filtration, Filter media
Filter aids and selection of filters
Study of the following filtration equipments-Filter Press, sintered filters, Filter candles, Metafilter.
Extraction and Galenicals
6
(a) Study of percolation and maceration and their modification, continuous hot extraction
Application in the preparation of tinctures and extracts
(b) Introduction to Ayurvedic dosage forms
Heat process-Evaporation
Definition-Factors affecting evaporation
study of evaporating still and Evaporating pan
Distillation
6
Simple distillation and Fractional distillation
steam distillation and vacuum distillation
Study of vacuum still
preparation of purified water I.P
preparation of water for Injection I.P
construction and working of the still used for the same
Introduction to drying process-
3
Study of Tray Dryers
Fluidized Bed Dryer
Vacuum Dryer and Freeze Dryer
Sterilization
6
Concept of sterilization and its differences from disinfection
Thermal resistance of microorganisms
Detailed study of the following sterilization process
Sterilization with moist heat, Dry heat sterilization
Sterilization by radiation
Sterilization by filtration and Gaseous sterilization
Aseptic techniques
2
Applications of sterilization process in hospitals particularly with reference to surgical dressings and intravenous fluids
Precautions for safe and effective handling of sterilization equipment
Processing of Tablets
8
Definition; different type of compressed tables and their properties
Processes involved in the production of tablets
Tablets excipients
Defects in tablets
Evaluation of Tablets
Physical standards including Disintegration and Dissolution
Tablet coating-sugar coating; films coating
enteric coating and micro-encapsulation
Processing of Capsules
4
Hard and soft gelatin capsules
different sizes of capsules
filling of capsules
handling and storage of capsules. Special applications of capsules.
Study of immunological products
1
sera, vaccines, toxoids & their preparations.
Their classification with examples-their relative applications
Description
Practice Questions
Additional Notes
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